EVALUATION OF ANTI–HIV–1 ACTIVITY OF CORDIA MYXA L. AND PHYTOCHEMICAL PROFILE

DOI: 10.7904/2068–4738–V(9)–51

Khaled RASHED, Meng–TING LUO, Lin–TAO ZHANG, Yong–TANG ZHENG  (EGYPT and CHINA)

Abstract. This study deals with evaluation of anti–HIV–1 activity from Cordia myxa stemsextracts and investigation of phytochemical content of the plant extracts. Dichloromethane, ethyl acetate, and methanol 80% extracts of Cordia myxawere tested for their anti–HIV–1 activity using the syncytia formation assay. All the extracts showed a weak anti–HIV–1 activity. Phytochemical analysis of the extracts proved the presence of the following phytochemicals, triterpenes in dichloromethane extract. Flavonoids and triterpenes in ethyl acetate extract. Carbohydrates, flavonoids, and triterpenes in methanol extract. This research work gave a brief note about main chemical constituents and anti–HIV–1–activity of Cordia myxa extracts.

 Key words: Cordia myxa, stems, cytotoxicity, anti–HIV–1 activity, phytoconstituents

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