Hong-Thien VAN 1#, Ngoc-Buu TRAN1#, Tran-Tien TRINH1, Nhu-Truc Thi VO1, Van-Son LE2, Tan-Viet PHAM1, Gia-Buu TRAN1, Tan-Quoc Pham LE1*
1Institute of Biotechnology and Food-technology, Industrial University of Ho Chi Minh City, 12 Nguyen Van Bao Street, Go Vap District, Ho Chi Minh City, VIETNAM
2Binh Chau-Phuoc Buu Nature Reserve, Bung Rieng ward, Xuyen Moc District, Ba Ria-Vung Tau Province, VIETNAM
*Corresponding author: firstname.lastname@example.org / #Both authors contributed equally to this work
Abstract. Amorphophalus lanceolatus is a rare member belonged to Araceae family and is recorded as an endemic species of Binh Chau–Phuoc Buu Nature Reserve (Vietnam). The phytochemical composition and antimicrobial activity of A. lanceolatus have not been studied yet. In this study, we determined the phytochemical composition of ethanol extract of A. lanceolatus tuber using liquid chromatography–mass spectrometry (LC–MS) and evaluated the antibacterial activity of ethanol extract via disk diffusion test. We identified 12 compounds in ethanol extract of A. lanceolatus tuber, such as polyethylene glycol–diglycidyl ether, lycopersin, heptacosane, n–heneicosylcyclopentane, homalomenol F, maltitol, pyrinuron, octadecane, 2 (1 H) naphthalenone, 3,5,6,7,8,8a–hexahydro–4,8a–dimethyl–6–(1–methylethenyl), 2–methylfluoranthene, quinic acid, 1H–imidazole. Moreover, we proved that ethanol extract of A. lanceolatus tuber could inhibit the growth of B. cereus, E. coli, P. aeruginosa, S. enteritidis, S. typhimurium, and S. aureus.
Keyword: antibacterial activity, A. lanceolatus, chemical composition, ethanol extract, LC–MS.