Chemical constituents and antibacterial activity of essential oil of Vitex rotundifolia from Southern Vietnam

DOI: 10.7904/2068-4738-XI(22)-22

 

Hong Thien VAN1*, Vo Thu Hien TRAN1, Nu Han Ni TON1, Thao Nguyen LUU1, Nguyen Tuong An HUYNH2, Van Son LE3

 1Institute of Biotechnology and Food–technology, Industrial University of Ho Chi Minh City, No. 12 Nguyen Van Bao Street, Go Vap District, Ho Chi Minh City, VIETNAM

2Office of Postgraduate Management, Industrial University of Ho Chi Minh City, No. 12 Nguyen Van Bao Street, Go Vap District, Ho Chi Minh City, VIETNAM

3Binh Chau–Phuoc Buu Nature Reserve, Bung Rieng Ward, Xuyen Moc District, Ba Ria–Vung Tau Province, VIETNAM

*Corresponding Author: vanhongthien@iuh.edu.vn

 Abstract. In present study, we identified the chemical composition of essential oil which was isolated from the leaves of Vitex rotundifolia using gas chromatography–mass spectrometry (GC–MS) analysis for the first time. A total of eighteen compounds were identified from essential oil, including sclareol (29.01 %); sandaracopimarinal (16.51 %); abietadiene (15.65 %); androsta–4,6–dien–3–one, 17–hydroxy–, (17β)– (8.12 %); abietal (6.45 %); dehydroabietan (5.02 %); verticiol (4.89 %) as major constituents. Furthermore, the antibacterial activity of the essential oils isolated from of the leaves of studied species has also been evaluated in the first time. The results proved that the essential oils could inhibit the growth of six pathogenic bacterial strains which the diameter of the growth inhibition zone of S. aureus, B. cereus, P. aeruginosa, S. enteritidis, S. typhimurium, E. coli were 27.3±0.6mm, 24.5±1.8mm, 24.3±0.8mm, 21.2±1.2mm, 8.8±0.3mm, 8.3±0.3mm, respectively.

Keyword: Vitex rotundifolia; GC/MS; antibacterial activities; essential oil.

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