Steliana RODINO1, Marian BUTU1*, Carmen GAIDAU2, Manuela CALIN3, Alina BUTU1
1National Institute of Research and Development for Biological Sciences, Bucharest, Romania,
2Leather and Footwear Research Institute, Bucharest, Romania,
3Institute of Cellular Biology and Pathology “Nicolae Simionescu”, Bucharest, Romania,
*Corresponding author, e–mail: marian firstname.lastname@example.org
Abstract. The development of in silico methods with application in scientific research is in full progress. They have the advantage of being modest consumers of material resources and time and, also, of being easy to be used by researchers from various field of specialization. The research work described in this paper has pursued building an ontological model for the evaluation of the impact of nanoparticle on the human cell. This model can be used to determine the inflammatory and cytotoxic effects of nanomaterials on human cells by complements and refining of the data achieved by well–known laboratory techniques.
Keyword: ontology, modelling, citotoxicity, nanoparticles.